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Monday, August 3, 2020 | History

2 edition of Studies on the immunogenetics of diabetes mellitus and its complications found in the catalog.

Studies on the immunogenetics of diabetes mellitus and its complications

Catherine Helen Mijovic

Studies on the immunogenetics of diabetes mellitus and its complications

by Catherine Helen Mijovic

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  • 10 Currently reading

Published by University of Birmingham in Birmingham .
Written in English


Edition Notes

Thesis (Ph.D.) - University of Birmingham, Dept of Immunology.

StatementCatherine Helen Mijovic.
ID Numbers
Open LibraryOL13902403M

  Diabetes is one of the world’s most prevalent and serious non-communicable diseases (NCDs). It is a leading cause of death, disability and financial loss; moreover, it is identified as a major threat to global development. The chronic nature of diabetes and its related complications make it a costly disease. Estimating the total cost of an illness is a useful aid to national and.   Increased awareness amongst large population groups is a major determinant for the prevention of diabetes and its complications as well as related metabolic disorders. Knowledge and attitude are the principal markers of awareness that need to be studied in various population groups in specific racial and cultural contexts. The present study was undertaken to explore knowledge, attitude .

  In this study respondents had responded correctly to diabetes affect any part of body (%), and defined as high level of sugar in the blood (49%) and is not curable (%).This study finding was higher than a study done in Debre Tabor where participants stated that diabetes mellitus is incurable (%), diabetes affects all parts of the. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Several pathogenic processes are involved in the development of.

Diabetes may affect the musculoskeletal system in a variety of ways. The metabolic perturbations in diabetes (including glycosylation of proteins; microvascular abnormalities with damage to blood vessels and nerves; and collagen accumulation in skin and periarticular structures) result in changes in the connective tissue. Musculoskeletal complications are most commonly seen in patients with a. Diabetes mellitus (DM) also known as simply diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period This high blood sugar produces the.


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Studies on the immunogenetics of diabetes mellitus and its complications by Catherine Helen Mijovic Download PDF EPUB FB2

Diabetes is a complex, progressive disease, which is accompanied by several complications. It is listed among the most common endocrine disorders and a global metabolic epidemic disease. This book focuses on the recent progress in diabetes research worldwide.

It has been written by extensively acknowledged experts, with each chapter providing a unique data on developing features of diabetes Author: R G Ahmed.

Journal of Diabetes and Its Complications(JDC) is a journal for health care practitioners and researchers, that publishes original research about the pathogenesis, diagnosis and management of diabetes mellitus and its complications.

JDC also publishes articles on physiological and molecular aspects of glucose homeostasis. Much of the confusion that has arisen from studies of the genetics of diabetes mellitus arises from the fact that, until recently, diabetes was regarded as a single disease.

It is now clear that there are at least two major types of diabetes which are aetiologically distinct, although they have similar long-term by: 1. Syed Khalid Imam FCPS, in Glucose Intake and Utilization in Pre-Diabetes and Diabetes, Conclusion.

Diabetes mellitus is growing to epidemic proportions, leading to devastating complications if not treated well. There are many challenges in the successful treatment of diabetes mellitus because of personal and economic costs incurred in diabetes therapy.

Aims and Scope The primary purpose of Journal of Diabetes and Its Complications is to act as a source of information, usable by those caring for patients with diabetes mellitus who are thereby at risk for development of those complications which all too often appear with time.

While our primary aim is to assist the practitioner in his/her care of such patients, and to afford access to. Introduction. Type 1 diabetes mellitus is a chronic autoimmune disease in which endogenous insulin production is severely compromised as a result of an immune-mediated injury of pancreatic β-cells (Eisenbarth, ).Genetic analyses of T1DM have linked the HLA complex, mainly class II alleles, to susceptibility to T1DM (Morel et al., ; Todd et al., ).

In Brief Acute care for patients with diabetes varies greatly depending on the nature of the patients’ primary illness and physical condition during hospitalization. The following two case studies review common considerations when treating 1) diabetic patients who develop infections; and 2) hyperglycemic inpatients who have had an acute myocardial infarction or cerebrovascular accident.

The specialized role of nursing in the care and education of people with diabetes has been in existence for more than 30 years. Diabetes education carried out by nurses has moved beyond the hospital bedside into a variety of health care settings.

Among the disciplines involved in diabetes education, nursing has played a pivotal role in the diabetes team management concept. Diabetes mellitus has large number of complications; some of them are well known such as nephropathy, and retinopathy, and neuropathy.

Diabetic foot has always been a point of worry for treating physicians but complications like diabetic hand syndrome might not have gained enough recognition. Studies conducted on the pathophysiology of diabetes mellitus suggested that abnormal metabolism of insulin hormone is the primary cause for the development of this complex syndrome.

Even though the etiologies and triggering factors of the three types of diabetes mellitus are different, they cause nearly the same symptoms and complications. Diabetes mellitus is a disease often called sugar diabetes because the condition makes it difficult to convert food to energy.

Long-term complications can affect many parts of your body. CORONAVIRUS: UPDATED VISITOR RESTRICTIONS, INCREASED SAFETY MEASURES + COVID TESTING. Diabetes is diagnosed by one of the following (see chart): Your blood sugar level is equal to or greater than mg/dl (7 mmol/l).

You have two random blood. Diabetes is a chronic health problem with devastating, yet preventable consequences. It is characterized by high blood glucose levels resulting from defects in insulin production, insulin action, or both.1,2 Globally, rates of type 2 diabetes were million in ,3 the number of people with diabetes.

The “Diabesity” epidemic (obesity and type 2 diabetes) is likely to be the biggest epidemic in human history. Diabetes has been seriously underrated as a global public health issue and the world can no longer ignore “the rise and rise” of type 2 diabetes. Currently, most of the national and global diabetes estimates come from the IDF Atlas.

Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time.

Symptoms often include frequent urination, increased thirst, and increased appetite. If left untreated, diabetes can cause many complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or.

The NIDDK-sponsored Diabetes Prevention Program (DPP) and ongoing DPP Outcomes Study (DPPOS) are major studies that changed the way people approach type 2 diabetes prevention worldwide.

The DPP showed that people who are at high risk for type 2 diabetes can prevent or delay the disease by losing a modest amount of weight through lifestyle. Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with increased health expenditure, and low quality of life.

Many non-genetic risk factors have been suggested, but their overall epidemiological credibility has not been assessed. Methods We searched PubMed to capture all meta-analyses and Mendelian randomization studies for risk factors of T2DM.

Diabetes is associated with a significant burden globally. The costs of diabetes-related hospitalizations are unknown in most developing countries.

The aim of this study was to estimate the total number and economic burden of hospitalizations attributable to diabetes mellitus (DM) and its complications in adults from the perspective of the Brazilian Public Health System in When diabetes is uncontrolled, it has dire consequences for health and well-being.

In addition, diabetes and its complications impact harshly on the finances of individuals and their families, and the economies of nations. People with diabetes who depend on life-saving insulin pay the ultimate price when access to affordable insulin is lacking. Type 1 diabetes is a chronic autoimmune disease.

Type 1 diabetes was previously called insulin-dependent diabetes mellitus (IDDM) or juvenile-onset diabetes. Type 1 diabetes develops when the body’s immune system destroys pancreatic beta cells, the only cells in the body that make the hormone insulin that regulates blood glucose.

Continued Protect Your Feet. Type 1 diabetes can take a toll on your feet. Nerve damage can make them numb or tingly, and it can weaken or destroy the tissue in them. Infections and ulcers are. In the study, the determinants of erectile dysfunction were; duration of diabetes mellitus, health insurance, site or health facility, level of education, and alcohol use.

The prevalence of erectile dysfunction due to diabetes mellitus worldwide occurs at 30% to .Type 1 diabetes mellitus (T1DM) is an autoimmune disease arising through a complex interaction of both genetic and immunologic factors.

Similar to the majority of autoimmune diseases, T1DM usually.